TRANQUILIZERS AND ANAESTHETICS
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1. Lignocain
Hydrochloride
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Class:
Local Anaesthetic
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Trade Name
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Composition
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Packing
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Company
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Recommended Dose
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Xylocain
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2%
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10 ml
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B & H
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As recommended
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Adecaine-adrenaline
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2% + adrenaline
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10 ml
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PDH
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As recommended
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2. Xylazine Hydrochloride
Class: Tranquilizer,
Alpha 2-agonist
Clinical use: include sedation,
analgesia, short term anaesthesia, and induction of vomiting.
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Antidote:
Yohimbine,
(Yobine) and Atipamezole (Antisedan)
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Horses:
0.1-1 mg/kg, IV
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or
0.5-1.0 mg/kg, IM or SC
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Ruminants: 0.05-0.1 mg/kg,
IV or
0.1-0.2 mg/kg, IM
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Trade Name
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Composition
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Packing
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Company
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Recommended
Dose
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Xylaz
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23.32 mg/ml
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25 ml
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Farvet
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LA=2.5-5 ml IV, or
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5-10 ml IM
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3. Medetomidine
Class: Tranquilizer,
Alpha 2-agonist
Clinical
use: facilitating
clinical examination, minor surgical procedure and minor dental procedure that
do not require intubation.
Notes: Generally used for
Dogs.
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Trade Name
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Composition
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Packing
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Company
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Domitor
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1 mg
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10ml
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Pfizer
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4. Propofol
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Class: Dialkylphenols(GABA-A
recepters)
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Notes:
No analgesia thatswhy it is used with any opiod e.g.
Fentanyl
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Trade Name
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Composition
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Packing
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Company
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Recommended
Dose
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Propfol
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10mg
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20ml
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Abott
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As recommended
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Diprivan
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10mg
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20ml
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ICI
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As recommended
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5.
Ketamine
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Class: NMDA receptor
antagonist
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Horses: 1.1mg/kg SD, IV
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Ruminants:
2mg/kg SD, IV or
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4mg/kg SD, IM
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Trade Name
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Composition
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Packing
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Company
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Recommended
Dose
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Ketasol
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50mg
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10 ml
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Indus
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As recommended
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Ketacil
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50mg
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10ml
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Mediceena
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As recommended
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Ketalite
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50mg
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10ml
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Elite Ph.
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As recommended
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6. Chloral Hydrate
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Class: Aldehydes
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Horses:
60-200mg/kg SD, IV
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Ruminants:
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Trade Name
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Composition
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Packing
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Company
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Recommended
Dose
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Apnotek Inj
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0.1mg
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5ml
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AngloPak
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As recommended
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Chloral Hydrate Pwd
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100%
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100gm
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Symans
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As recommended
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2007-va-18
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š ANTIPROTOZOAL
DRUGS
1. Imidocarb Dipropionate
Clinical use: For
treatment of Babesiosis and Anaplasmosis.
Side
effects: May cause injection pain and mild cholinergic signs, such
as salivation, nasal drip or vomiting. Other less common side effects
are panting, restlessness, and diarrhea
Solution:
Severe
signs may be reversed with atropine sulfate. Notes: Second Dose must be
repeated after 48 Hrs
Horses: For Babesia:3mg/kg IM for 24Hrs
Ruminants: For
Babesia: 1.2 mg/kg SC SD ; For Anaplasma: 3mg/kg SC ;
For Prophylaxis: 3mg/kg SC
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Trade Name
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Composition
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Packing
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Company
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Recommended Dose
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Imizol
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120 mg/ml
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100 ml
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ICI
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C,S,G=1ml/100kg;
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H=1ml/50 kg
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Imipro
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120 mg/ml
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10 & 100 ml
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Selmore PH
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Same as Above
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Imido G
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120 mg/ml
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10 & 100 ml
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Zaidis Int.
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Same as Above
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Imicarb
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120 mg/ml
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50 & 100 ml
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Star
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Same as Above
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2. Diminazine Aceturate (also added
Phenazone for decreasing body temp.):
Clinical use: For Trypanosomiasis
(Good against T.congolense and T.vivax but not so much effective against
T.brucei)
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Horses:
3-5mg/kg IM (But much toxic to Horses as compared to
cattle)
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Ruminants: 3-5mg/kg IM
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Trade Name
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Composition
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Packing
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Company
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Recommended Dose
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Tryptowan
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1.05 gm + 1.31gm
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2.36gm +15 ml
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Nawan
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Babesia=1ml/40kg;
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H2O
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Trypanosoma=1ml/20kg
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Trichomonas =1ml/20kg
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Dimirin
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1.05 gm + 1.31gm
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50 & 100 ml
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Zaidi bros.
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0.3ml
/ 10kg
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Diminol (2.36gm)
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1.05 gm + 1.31gm
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Sachet
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Star
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As recommended
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Diminol (9.44gm)
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4.2gm
+ 5.24gm
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Sachet
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Star
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As recommended
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3. Diminazine
Diaceturate
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Clinical
use: For treatment of Trypanosomiasis and Babesiosis.
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Notes: Second Dose must be
repeated after 48 Hrs
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Horses:
3-5mg/kg IM Sid
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Ruminants: 3-5mg/kg IM Sid
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Brand Name
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Composition
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Packing
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Company
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Recommended Dose
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Fatribanal RTU
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35 mg/ml
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50 ml
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Fatro
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1 ml/20 kg
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Fatribanal
Sachet (14gm)
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-
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Single Dose
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Fatro
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15 ml Sol
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Diminazin
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35 mg/ml
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50 ml
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Star
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1 ml/20 kg
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Diminazine DS
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70mg/ml
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50, 100ml
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Star
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As recommended
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4. Buparvaquine
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Clinical use: For treatment of
theileriasis.
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Horses:
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Ruminants: 2.5mg/kg IM Sid
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Brand Name
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Composition
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Packing
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Company
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Recommended
Dose
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Butalax
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50 mg
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20ml
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ICI
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1 ml/20 kg
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Parvon
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50 mg
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20ml
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Selmore
Ph.
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Same as Above
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Buparvalax
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50 mg
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50, 100ml
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Star
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Same as Above
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5.
Quinapyrimine Sulphate + Quinapyrimine Chloride
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Notes:
Drug of choice for T.brucei and less toxic to horses as
compared to diminazine.
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Brand Name
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Composition
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Packing
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Company
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Recommended
Dose
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Biquin
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1.5gm+1gm
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(2.5gm
)20ml SD
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Star
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1 ml/20 kg
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