ANTIPYRETIC, ANALGESICS AND ANTI-INFLAMMATORY DRUGS

ANTIPYRETIC, ANALGESICS AND ANTI-INFLAMMATORY DRUGS

1. Methampyron + Aminopyrine + Caffeine + Chlorpheniramine

Indications: Causes Analgesia for mild to moderate pain, Antiinflammatory action and Antipyretic.

Trade Name
Composition
Packing
Company
Recommended Dose
Thampyron
100+10mg+1mg+10mg
50 ml
Atzan
Ls = 20 ml ;Ms =10 ml;




Ss=5 ml
Strongpyrone
200+50+20+2mg
50 ml
Selmore AG
Same as Above
Metapyron
-
50 ml
Zaidis Int.
Same as Above
Pyrosel
200+50+20+2mg
50 ml
Selmore Ph
Same as Above

2. Phenylbutazone

Class: Pyrazolidine derivative

Indications: Used extensively in horses for treatment of lameness, and for relief of pain with colic. Actions: Causes Analgesia for mild to moderate pain, Anti-inflammatory action and Antipyretic. Side effects: Causes GIT ulcers and bone marrow suppression.
Notes: Should be given IV.


Horses: 2-4.4 mg/kg IV
Sid, Bid
Ruminants: 4mg/kg IV Sid






Trade Name
Composition
Packing
Company

Butadin
2 gm/10 ml
10 & 100 ml
Star

Pain Go
Same
50, 100ml
Leads Ph.

Phenadine
Same
100ml
Biorex

Elkazolidine
Same
Same
Elko Org.

3. Diclofenic Sodium

Class: Heteroaryl acetic acids

Notes: Getting banned due to its residual problem and Vultures death issues.

Trade Name
Composition
Packing
Company
Dicloran
25mg/ml
3ml amp
Sami
Voren
25mg/ml
3ml amp
Continental
Voltral
25mg/ml
3ml amp
Novartis

4. Flunixin Meglumin

Class: Banamine derivative

Indications: Pain associated with musculo-skeletal disorders and colic. Other uses are endotoxic shock, calf diarrhea,
heat stroke and opthalamic infections.





Side effects: In horses, include swelling at injection site, and sweating.


Horses: 0.25-1 mg/kg IM

Ruminants: 1.1-2.2 mg/kg IM









Trade Name
Composition
Packing

Company
Recommended Dose

Loxin
50 mg/ml
10
& 20 ml

Selmore PH
2 ml/45 kg

Fluen
50 mg/ml
10
&20 ml

Vetycare
2 ml/45 kg

5. Meloxicam

Class: Oxicam derivatives

Indication: Inflammatory muscular pain, fever, chronic musculo skeletal disorders & soft tissue injury. Also effective in pneumonia, bronchopneumonia, mastitis, prolapse of uterus and vagina.

Horses: Not used

Ruminants: 0.5mg/kg IM








Trade Name
Composition
Packing
Company
Recommended Dose

Metrym
20 mg/ml
10, 20 & 50 ml
Nawan
1 ml/40 kg

Vetafenac plus
7.5 mg/ml
10 & 50 ml
SJ & G
Same as Above

Melacam
20mg
50, 100ml
Medivet
Same as Above

Diclostar
Same
50ml
Star
Same as Above












6. Ketoprofen
















Class: Propoinic acid derivative.












Horses: 2.2 mg/kg, IV, sid


Ruminants: 2.2 mg/kg, IV; 3 mg/kg, IM, sid






















Trade Name


Composition

Packing
Company

Recommended Dose



Profenid


50mg;

2ml amp
Rhone-Poulenc

As recommended













Rorer







Ketoject


100mg

50ml
Selmore Ph.

As recommended



7. Metamizol Sodium
















Class: Pyrazolidine derivative












Indications: should be used in severe pain and fever.









Notes: Reported to cause agranulocytosis












Horses: 11-22mg/kg






Ruminants: 50mg/kg

























Trade Name


Composition


Packing


Company


Recommended Dose



Dipyron


1gm/2ml


50,100ml


Symans


LA=3ml/100kg

















SA=1ml/40kg



Dipysym


500mg/2ml


50,100ml


Symans


Same as Above



Novalgin


500mg/2ml


5ml amp.


Hoechst


Same as Above


8. Oxytetracycline + Mepyramine + Phenylbutazone


























Trade Name

Composition

Packing

Company


Recommended Dose



Phenoxy

50+25+25mg

20ml,50ml

Selmore Ph.


15ml/animal



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