Hormonal drugs avaiable in the Pakistani markete

 

Hormonal drugs avaiable in the markete

A) Estrogen Preparations:-

Clinical use: for treating persistent CL, for expelling purulent material from the uterus, retained placenta and

mummified fetus, and for promoting weight gain.

 

1. Stilboesterol Dipropionate:-

Horses: 0.3mg/kg

Ruminants:heat:2-3cc,retained placenta:30-50mg,pyometra 20- 25mg.

Trade Name	Packing	Company
Stilbosterol	10 ml	star

 

2. Estradiol Dipropionate:-

Horses: 1mg/kg (for estrus induction 15mg/kg TD)

Ruminants: 4-10mg/kg Sid IM

Trade name	packing	Company
Agofollin	15 ml	Pfizer

 

 

 

 

B) Progestrone Preparations:-

Clinical Use: For extra supply of progesterone to establish pregnancy,decrease sex desire,estrus synchronization,

Horses: 0.3-0.6 mg/kg

Ruminants

Trade name	Packing	Company
Pregtone	10ml	Selmore Ph.
Progestrone	10ml	Star

 

C) FSH Preparations:-

Clinical Use: For stimulation of follicles,For estrus synchronization

Horses: 10-50mg/kg SD

Ruminants: 5mg/kg TD

Trade name	packing	Company
sigma	2ml,10ml	Sigma Aldrich Co.

 

 

 

D) Prostaglandins Preparations:-Clinical Use: For estrus synchronization, For Follicular and Luteal Cysts,regression of CL.

1. Cloprostinol Sodium:

Horses: 0.1mg/kg TD

Ruminants: 0.5-O.13mg/kg TD

Trade name	packing	Company
prostinol	2ml	Selmore PH
clostinol	2ml	Zaidis Int.
cyclomate	2ml	Star
delmazine	2ml,10ml	Fatro

 

2. Dinoprost Tromethanine(Natural):-

Horses:0.002-0.01mg/kg SD     

Ruminants: 25mg/kg

Trade name	packing	Company
lutalyse	5ml	upJohn

 

E) GnRH Preparations:-

Clinical use:estrus synchronization,induction of ovulation,infertility in females,for lebido in male

 

1. Lecirelin Acetate:

Horses:    0.04 mg/kg                                 

Ruminants:0.02 mg/kg

Trade name	packing	Company
Dalmarelin	2ml	fatro

 

2. Buserelin Acetate:

Horses: 0.04 mg/kg            

Ruminants: 0.02 mg/kg

Trade name	packing	Company
conceptal	2ml	Star

 

F) Oxytocin Preperations:-

Clinical use: To increase uterine contractions during delivery, to aid in the delivery of placenta, to facilitate the involution of uterus, and to induce milk let down.

Horses: Retained Placenta……0.01-0.02 mg/kg

Ruminants: Retained Placenta……0.05-0.1 mg/kg

Milk Let down……….0.025- 0.05 mg/kg

 

Oxytocin LP	1 & 50ml	lawrence
oxytocin	50ml	orient
Oxytocin IPL	50ml	IPL
Oxytocin VP	50ml	venus
Oxytocin KAK	50ml	kakasian
Oxytocin S	50ml	star

 

G) bST Hormone:-

Clinical use:growth hormone so use to increase the milk production and it causes 10-15% increase in milk production.

Notes: High dosages of bST are reported to increase the death rate of calf embryos, so starting a cow on bST during early pregnancy should probably be avoided.

Trade name	company	Recommended dose
Somatech s/c               Boostin	ICI	one syringe every 14 days.Start during the 9th or 10th week after calving and continue until the end of lactation.

 

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Veterinary Hormonal Drugs Available in Market

Veterinary Hormonal Drugs Available in Market 

A) Estrogen Preparations

Clinical use: for treating persistent CL, for expelling purulent material from the uterus, retained placenta and mummified fetus, and for promoting weight gain.

Side effects: cause anemia, prolonged estrus, genital irritation and follicular cysts.

Caution: Estrogens should not be given during pregnancy and always used alongwith oxytocin.

1. Stilboesterol Dipropionate
	Horses: 0.3mg/kg							Ruminants:
	Trade Name			Composition		Packing		Company	Recommended Dose
	Stilbosterol			10 mg/ml		10 ml		Star	Ls=10 ml, Ms =4ml
									Ss=2ml
2. Estradiol Dipropionate
	Horses: 1mg/kg	(for estrus induction 15mg/kg TD)						Ruminants: 4-10mg/kg Sid IM
	Trade Name			Composition		Packing		Company	Recommended Dose
	Agofollin			1 mg/ml		15 ml		Pfizer	Ls=5 ml, Ms=1 ml
									Ss=0.5 ml

B) Progestrone Preparations

Clinical Use: For extra supply of progesterone.
Horses: 0.3-0.6 mg/kg		Ruminants:
Trade Name	Composition	Packing	Company	Recommended Dose
Progestrone	25 micro-g/ml	10ml	Star
Pregtone	25 micro-g/ml	10ml	Selmore Ph.

C) FSH Preparations

Clinical Use: For stimulation of follicles,For estrus synchronization
Horses: 10-50mg/kg SD		Ruminants: 5mg/kg TD
Trade Name	Composition	Packing	Company	Recommended Dose
Sigma	50units	2 ml,10ml	Sigma Aldrich Co.	Ls=2.5-5 ml Ss=1-2
				ml

D) Prostaglandins Preparations

Clinical Use: For estrus synchronization, For Follicular and Luteal Cysts.

Side Effects: Should not be used in Pregnancy

1. Cloprostinol Sodium
	Horses: 0.1mg/kg TD				Ruminants: 0.5mg/kg(C) O.13mg/kg(S,G) TD
	Trade Name		Composition	Packing		Company	Recommended Dose
	Prostinol		263 micro gm	2 ml		Selmore PH	Ls=2 ml Ms=1 ml
			/ml				Ss=0.5 ml
	Clostinol		263 micro gm	2 ml		Zaidis Int.	Same as Above
			/ml
	Cyclomate		263 micro gm	2 ml		Star	Same as Above
			/ml
	Dalmazine		75 micro gm	2 ml, 10ml		Fatro	Same as Above
	(dextro-rotatory)		/ml

Created by : Furqan Awan

2007-va-18

2. Dinoprost Tromethanine(Natural):

Horses:0.002-0.01mg/kg SD

Ruminants: 25mg/kg(C) See Table from D.C. Blood

Trade Name

Composition

Packing

Company

Recommended Dose

Lutalyse

5 micro-g/ml

5ml

UpJohn

Ls=5 ml / condition

E) GnRH Preparations

1. Lecirelin Acetate

Horses:

Ruminants:

Trade Name

Composition

Packing

Company

Recommended Dose

Dalmarelin

25 micro-g/ml

2 ml

Fatro

Ls=2-4 ml

Ss=1-2 ml / condition

2. Buserelin Acetate

Horses: 0.04 mg/kg

Ruminants: 0.02 mg/kg

Trade Name

Composition

Packing

Company

Recommended Dose

Conceptal

4.2 micro-g/ml

2 ml

Star

Ls=2.5-5 ml

Ss=1-2 ml / condition

F) Oxytocin Preperations

Clinical use: To increase uterine contractions during delivery, to aid in the delivery of placenta, to facilitate the involution of uterus, and to induce milk let down.

Side effects: are minimal when used according to recommendation

Horses: Retained Placenta……0.01-0.02 mg/kg

Ruminants: Retained Placenta……0.05-0.1 mg/kg Milk Let down……….0.025- 0.05 mg/kg

Trade Name	Composition	Packing	Company	Recommended Dose
Oxytocin LP	10 IU/ml	1 & 50 ml	Lawrence	L=1-2 ml S=0.5-1 ml
Oxytocin	10 IU/ml	50 ml	Orient	Same as Above
Oxytocin VP	10 IU/ml	50 ml	Venus	Same as Above
Oxytocin IPL	10 IU/ml	50 ml	IPL	Same as Above
Oxytocin KAK	10 IU/ml	50 ml	Kakasian	Same as Above
Oxytocin S	10 IU/ml	50 ml	Star	Same as Above

G) bST Hormone:

Notes: High dosages of bST are reported to increase the death rate of calf embryos, so starting a cow on bST during early pregnancy should probably be avoided

Trade Name	Composition	Packing	Company	Recommended Dose
Somatech INJ	500 mg of	SD	ICI	one syringe every 14
(S/C)	sometribove			days.Start during the
	zinc			9th or 10th week after
				calving and continue
				until the end of
				lactation.

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