Aminoglycosides (Gentamicin,
Kanamicin, Amikacin, Streptomycin, Neomycin) With trade name
Class:
Bacteriocidal,
Broad Spectrum Mechansim: Irreversibly bind to the 30S ribosome
Indications: Infections caused by
susceptible pathogens, pneuomonias, urinary tract infections, endometritis, and
septicemias that are resistant to other antibiotics.
Antagonists: Amphotericin
B, Cephalosporins produce nephrotoxicity.
Side effects: Intestinal flora may
be disrupted, diarrhea may occur. Other includes intramuscular blockage (when used
with anaesthetic agents), nephrotoxicity and ototoxicity (oto=ear)
Notes: These are used in all species.
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1.
Gentamycin
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Horses:
3-6mg/kg BID IM
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Ruminants: 3-6mg/kg BID IM
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Trade name
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Composition
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Packing
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Company
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Genton
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100 mg/ml
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50 & 100 ml
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ICI
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Gentasel – 10
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100 mg/ml
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50 & 100 ml
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Selmore PH
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Medi G 10
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100 mg/ml
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50 & 100 ml
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Medivet
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Gentasal 100
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100 mg/ml
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50 & 100 ml
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Atzan
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Gentafar
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100 mg/ml
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50 & 100 ml
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Farvet
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Gentawan – 10
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100 mg/ml
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100ml
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Nawan
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Gentalin – 10
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100 mg/ml
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50,100ml
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Star
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Gentasal - 50
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50 mg/ml
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100 ml
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Atzan
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2. Gentamycin +
Trimethoprim + Sulfonamide
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Trade name
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Composition
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Packing
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Company
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Recommended
Dose
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Genta plus
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30+125+25
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50,100ml
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Leads Ph.
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First
Dose=30ml/50kg
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mg/ml
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2nd
Dose=15ml/50kg
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3. Tylosin +
Gentamycin
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Trade name
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Composition
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Packing
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Company
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Recommended
Dose
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Tylogent
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100 + 50 mg/ml
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50, 100ml
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Eterna
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LA=1ml/30kg
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SA=1ml/20kg
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4.
Kanamycin
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Notes: More good effects in
Dogs & cats. Excessive dose can effect in 8th
Cranial Nerve.
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Horses:
12-15mg/kg IM
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Ruminants: 12-15 mg/kg IM
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Trade name
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Composition
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Packing
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Company
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Kanasym
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100 mg/ml
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50,100ml
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Symans
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Kanacon
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100 mg/ml
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50,100ml
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Vetcon
Ph.
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Kana Kak
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100 mg/ml
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50 ml
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Trust Pharma
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Kanamycin
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100mg/ml
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10,
50ml
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China
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Kanachron
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100 mg/ml
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10
& 50 ml
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Star
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5. Kanmycine + Ampicillin
+ Prednisolone +
Chlorpheniramine
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Trade name
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Composition
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Packing
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Company
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Recommended
Dose
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Kapcine
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100mg+200mg+10mg+4mg
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50,
100ml
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Leads Ph.
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LA=1ml/20kg
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SA=1ml/10kg
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